Home / Services / Mental Health Treatments / Ketamine Therapy
Welcome to our ketamine infusion clinic located in the heart of Colorado Springs, CO. We understand that seeking treatment for mental health or chronic pain conditions can feel overwhelming, and we are here to provide a supportive, compassionate environment where your healing journey is our priority. Our clinic specializes in ketamine therapy, a cutting-edge treatment option that has shown promising results for individuals struggling with depression, anxiety, PTSD, and certain pain syndromes. Whether you are new to ketamine or exploring alternative therapies, our team is dedicated to guiding you through every step with clarity and care.
Our clinic in Colorado Springs is designed to be a welcoming space where patients feel safe and respected. We combine clinical expertise with a warm, trauma-informed approach to care, ensuring that each person’s unique needs are met with sensitivity and professionalism. The environment is calm and private, allowing you to relax during your treatment sessions and focus on your well-being.
We prioritize patient education and open communication, so you always understand your treatment plan and what to expect. Our goal is to empower you with knowledge and support, helping you make informed decisions about your health in a nonjudgmental setting.
Our medical team is composed of board-certified physicians and psychiatrists who specialize in ketamine therapy and mental health care. Each provider brings extensive experience in administering ketamine infusions safely and effectively. They stay current with the latest research and best practices to ensure that your treatment is grounded in the most up-to-date clinical evidence.
Beyond their credentials, our clinicians are deeply committed to compassionate care. They take the time to listen to your story, understand your goals, and tailor treatment plans that align with your individual health profile. This personalized approach helps optimize outcomes and fosters a trusting therapeutic relationship.
The ketamine infusions at our clinic are administered by skilled IV nurses who are specially trained in this therapy. They monitor your vital signs and comfort throughout each session, ensuring your safety and well-being at all times. Their expertise allows them to respond promptly to any concerns or side effects that may arise during treatment.
Our nurses also provide emotional support and reassurance, recognizing that ketamine infusions can be an intense experience for some patients. They create a calm and supportive atmosphere, helping you feel at ease from the moment you arrive until your session concludes.
Ketamine therapy is an innovative treatment that has gained recognition for its rapid and robust effects on mood and pain symptoms. Originally developed as an anesthetic, ketamine is now used in lower doses to target conditions that have not responded well to traditional treatments. It offers hope for many individuals who have struggled with persistent depression, anxiety, PTSD, or chronic pain.
Unlike conventional antidepressants that may take weeks to show benefits, ketamine often produces noticeable improvements within hours or days. This rapid action can be life-changing for those facing severe symptoms or suicidal thoughts. The therapy is typically delivered through intravenous infusions in a controlled clinical setting, allowing for close monitoring and adjustment as needed.
Ketamine’s mechanism of action is distinct from most other psychiatric medications. It primarily acts as an NMDA receptor antagonist, which means it blocks certain receptors in the brain that regulate glutamate, a key neurotransmitter involved in neural communication. By modulating glutamate activity, ketamine promotes a cascade of neurochemical events that enhance synaptic plasticity—the brain’s ability to form new connections and pathways.
This increase in neuroplasticity is believed to underlie ketamine’s rapid antidepressant effects. It helps “reset” dysfunctional neural circuits associated with mood disorders and pain processing. Additionally, ketamine influences other neurotransmitter systems and inflammatory pathways, contributing to its broad therapeutic potential.
Research continues to explore the full range of ketamine’s effects on the brain, but its unique action on glutamate and neuroplasticity sets it apart from traditional treatments and offers new avenues for recovery.
Ketamine therapy can be administered in different forms, with intravenous (IV) infusions and Spravato (esketamine) nasal spray being the most common. IV ketamine infusions deliver the medication directly into the bloodstream, allowing precise control over dosage and infusion rate. This method is typically performed in a clinic under medical supervision, providing a safe environment for monitoring and support.
Spravato, approved by the FDA for treatment-resistant depression, is a nasal spray version of esketamine, a derivative of ketamine. It offers a more convenient administration route and can be used alongside oral antidepressants. However, Spravato requires administration in a certified healthcare setting due to potential side effects and the need for observation post-dose.
Both treatments have demonstrated effectiveness, but the choice between IV ketamine and Spravato depends on individual patient factors, preferences, and clinical recommendations. Our team will help you understand the differences and determine the best approach for your needs.
Deciding whether ketamine therapy is appropriate involves a thorough evaluation of your medical history, current health status, and treatment goals. Ketamine is not a one-size-fits-all solution, and careful screening helps ensure safety and maximize benefits. Our clinic follows a trauma-informed, patient-centered approach to assess eligibility and tailor treatment plans accordingly.
We recognize that mental health and chronic pain conditions are complex and multifaceted. Our evaluation process includes detailed discussions about your symptoms, previous treatments, and any underlying medical or psychiatric conditions. This comprehensive assessment allows us to identify potential contraindications and develop a personalized care strategy.
Extremely educated about Ketamine therapy. My depression symptoms improved, despite the exorbitant cost.
C.F.
Google
Extremely educated about Ketamine therapy. My depression symptoms improved, despite the exorbitant cost.
R.H.
Google
Dr. Clay has given me my life, family, and friends back to me. When I first started seeing Dr. Clay, I was so depressed and anxious that I didn’t go out of the house. Dr. Clay’s medical assistant on my first appointment told me that he would never give up on me and he never has. Flash forward to now, and I’m seeing my friends, family, going out to run errands on my own, and even going to see my beloved sister in Colorado March 1st with our daughter. I am SO thankful for Dr. Clay and his team at Serenity Mental Health. They are a huge blessing and I feel so lucky to have found them!
k.
Google
My psychiatrist is named Dr. Colvin and he is an excellent person to count on for aid with mental health. He has prescribed medicine for me that has worked wonders in my life, and he continues to meet my concerns by providing more medication when needed. Alongside him, the staff is extremely flexible with their availability, and whenever I’ve needed to change a date on the calendar for appointments, they have been swift and generous to meet those needs as well. I’d recommend Serenity to anyone that is struggling to battle the demons in their head; they have changed my life and I know they will do the same for you as well.
K.D.
Google
Tolulope’s experience with TMS therapy has been excellent. She is patient and really kind, even if the initial consultation took some time to schedule.
M.V.
Google
Ketamine therapy may be suitable for individuals with treatment-resistant depression, anxiety disorders, PTSD, bipolar depression, and certain chronic pain syndromes. However, it is not recommended for everyone. Contraindications include uncontrolled hypertension, certain cardiovascular conditions, history of psychosis or schizophrenia, and active substance use disorders. Pregnant or breastfeeding individuals should also discuss risks carefully with their provider.
Before beginning treatment, patients undergo a thorough medical and psychiatric evaluation, including physical examination and relevant laboratory tests.
This process helps identify any risks and ensures that ketamine therapy is a safe option. Our clinicians also review current medications to avoid potential interactions and provide guidance on managing coexisting health issues.
Open communication and honesty during this evaluation are essential. Our team is here to support you without judgment and to help determine the best path forward based on your unique circumstances.
Our ketamine infusion protocol is designed to balance safety, efficacy, and patient comfort. We follow evidence-based guidelines and customize treatment plans to meet individual needs. The protocol includes an initial series of infusions followed by maintenance sessions as needed to sustain therapeutic benefits.
Throughout the treatment course, we closely monitor your response and adjust dosing or scheduling accordingly. Our goal is to provide a structured yet flexible approach that supports your healing journey while minimizing side effects and risks.
The typical ketamine infusion series consists of six treatments administered over two to three weeks. Each infusion lasts approximately 40 minutes to an hour, during which you will be comfortably seated or reclining in a quiet room. Initial doses are conservative and may be gradually increased based on your response and tolerance.
After completing the initial series, many patients experience significant symptom relief. To maintain these improvements, periodic booster infusions may be recommended. The frequency of maintenance treatments varies depending on individual needs and clinical judgment, ranging from monthly to quarterly sessions.
Our clinicians carefully evaluate your progress throughout the protocol and collaborate with you to determine the optimal dosing schedule. This personalized approach helps maximize benefits while minimizing potential side effects.
Before each infusion, you will have a brief check-in to review your current health status and any changes since your last visit. Vital signs such as blood pressure and heart rate will be measured to ensure it is safe to proceed. Our team will answer any questions and provide reassurance to help you feel comfortable.
During the infusion, you may experience mild dissociative effects, such as altered perception or a sense of detachment. These sensations are typically transient and well-tolerated. Our nurses remain with you throughout the session to monitor your condition and provide support.
After the infusion, you will rest in a recovery area until any side effects subside and you feel ready to leave. It is important to have a responsible adult accompany you home, as driving or operating machinery is not advised for several hours post-treatment. We provide detailed post-infusion care instructions to promote safety and comfort.
Preparing for your initial ketamine infusion visit helps ensure a smooth and positive experience. We provide clear guidance on what to do in the days leading up to treatment and on the day itself. Following these instructions supports your safety and enhances the effectiveness of therapy.
Our team is available to answer any questions you may have about preparation, so you feel confident and informed before your first session.
We recommend avoiding alcohol, recreational drugs, and certain medications that may interfere with ketamine treatment in the 24 hours before your infusion. Your provider will review your current medications and advise you on any adjustments needed. It is important to follow these guidelines closely to reduce risks and optimize treatment response.
Fasting is typically required for at least four hours before your infusion to minimize the risk of nausea or vomiting. You may have clear liquids up to two hours before your appointment unless otherwise instructed. Staying hydrated is encouraged, but avoid heavy meals immediately prior to treatment.
Because ketamine can impair coordination and judgment, you must arrange for a responsible adult to drive you to and from the clinic. This ensures your safety during the vulnerable period following the infusion.
Comfort is key during your infusion sessions. We suggest wearing loose, comfortable clothing that allows you to relax fully. Layers are helpful in case the treatment room temperature varies. Bringing a blanket or pillow is optional but can enhance your comfort during the infusion.
It is helpful to bring a list of your current medications, any relevant medical records, and your insurance information if applicable. Having these documents on hand facilitates a smooth check-in process and ensures accurate treatment planning.
Some patients find it beneficial to bring headphones and calming music or guided meditation apps to help create a soothing environment during the infusion. Our staff can also provide support and suggestions to help you feel at ease throughout your visit.
Ketamine therapy is rapidly transforming the landscape of mental health
Suicidal thoughts can be one of the most overwhelming and
Medication is a powerful tool in mental health treatment, but